MRSU 1155 – From Rare Kidney Diseases to Frequent Diseases, Remodelling and Repair

The main objective of our unit is to provide a comprehensive approach to the mechanisms responsible for loss of renal function and tissue repair and to develop more effective and specific treatments against progressive renal failure in order to halt the ever-increasing number of people requiring dialysis or transplantation. Our research projects primarily address clinically relevant questions. Most basic research programs aim to be translated into clinical applications, and inversely observations made at the bedside fuel novel research programs such as those devoted to rare diseases, to complications following Acute Kidney Injury, those associated to biocrystallisation/lithiasis, or those aiming to identify novel biomarkers and to provide innovative strategies for therapy. Our research goes beyond the borders of Nephrology since it addresses questions affecting several other organs and pathologies such as inflammation, fibrosis, endothelial dysfunction or abnormal cell proliferation.